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An essential role of NF-κB in the “tumor-like” phenotype of arthritic synoviocytes

A hallmark of rheumatoid arthritis is the formation of an aggressive, tumor-like structure called pannus that erodes the joint. A major cellular component of the pannus is the fibroblast-like synoviocyte (FLS), whose morphology strikingly resembles that of a transformed cell, but underlying mechanis...

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Detalhes bibliográficos
Main Authors: Li, Xiangli, Makarov, Sergei S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1859946/
https://ncbi.nlm.nih.gov/pubmed/17088540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607939103
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