Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases

Autoreactive memory T lymphocytes are implicated in the pathogenesis of autoimmune diseases. Here we demonstrate that disease-associated autoreactive T cells from patients with type-1 diabetes mellitus or rheumatoid arthritis (RA) are mainly CD4(+)CCR7(−)CD45RA(−) effector memory T cells (T(EM) cell...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Beeton, Christine, Wulff, Heike, Standifer, Nathan E., Azam, Philippe, Mullen, Katherine M., Pennington, Michael W., Kolski-Andreaco, Aaron, Wei, Eric, Grino, Alexandra, Counts, Debra R., Wang, Ping H., LeeHealey, Christine J., S. Andrews, Brian, Sankaranarayanan, Ananthakrishnan, Homerick, Daniel, Roeck, Werner W., Tehranzadeh, Jamshid, Stanhope, Kimber L., Zimin, Pavel, Havel, Peter J., Griffey, Stephen, Knaus, Hans-Guenther, Nepom, Gerald T., Gutman, George A., Calabresi, Peter A., Chandy, K. George
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2006
विषय:
Biological Sciences
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1859943/
https://ncbi.nlm.nih.gov/pubmed/17088564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605136103
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