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A single mutation in the castor Δ(9)-18:0-desaturase changes reaction partitioning from desaturation to oxidase chemistry

Sequence analysis of the diiron cluster-containing soluble desaturases suggests they are unrelated to other diiron enzymes; however, structural alignment of the core four-helix bundle of desaturases to other diiron enzymes reveals a conserved iron binding motif with similar spacing in all enzymes of...

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Autors principals: Guy, Jodie E., Abreu, Isabel A., Moche, Martin, Lindqvist, Ylva, Whittle, Edward, Shanklin, John
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1859913/
https://ncbi.nlm.nih.gov/pubmed/17088542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607165103
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