Anti-thrombotic effects of a nitric oxide-releasing, gastric-sparing aspirin derivative.

Effects of a nitroxybutylester derivative of aspirin (NCX 4215) on platelet aggregation and prostanoid synthesis were compared to the effects of aspirin. NCX 4215 was approximately seven times more potent than aspirin as an inhibitor of thrombin-induced human platelet aggregation in vitro, but did n...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wallace, J L, McKnight, W, Del Soldato, P, Baydoun, A R, Cirino, G
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1995
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC185978/
https://ncbi.nlm.nih.gov/pubmed/8675638
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