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Inhibitory effect of porcine surfactant on the respiratory burst oxidase in human neutrophils. Attenuation of p47phox and p67phox membrane translocation as the mechanism.

Surfactant has been shown to inhibit the production of reactive oxygen intermediates by various cells including alveolar macrophages and peripheral blood neutrophils. Superoxide O2-. production by the respiratory burst oxidase in isolated plasma membranes prepared from PMA-treated human neutrophils...

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Опубликовано в::J Clin Invest
Главные авторы: Chao, W, Spragg, R G, Smith, R M
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 1995
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185971/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8675631/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118331
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