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Effect of gentamicin treatment on adenylate cyclase and Na+, K+-ATPase activities in renal tissues of rats.

Gentamicin (20 mg/kg) treatment of male rats reduced Na+,K+-ATPase activity by 32% in renal cortical plasma membranes. In contrast, adenylate cyclase stimulation by isoproterenol or a guanyl nucleotide or both was enhanced by as much as twofold in glomeruli and in plasma membranes of gentamicin-trea...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Queener, S F, Luft, F C, Hamel, F G
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185949/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6318658/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.24.5.815
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