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Rifampin affects polymorphonuclear leukocyte interactions with bacterial and synthetic chemotaxins but not interactions with serum-derived chemotaxins.

Three independent experimental approaches support the hypothesis that rifampin competes for receptors on polymorphonuclear leukocytes (PMLs) with small peptide chemoattractants, e.g., N-formylmethionylleucylphenylalanine (FMLP), but not with serum-derived chemoattractants (C5a). First, rifampin inhi...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Gray, G D, Smith, C W, Hollers, J C, Chenoweth, D E, Fiegel, V D, Nelson, R D
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185941/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6318656/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.24.5.777
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