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Human and rat beta cells differ in glucose transporter but not in glucokinase gene expression.

Glucose homeostasis is controlled by a glucose sensor in pancreatic beta-cells. Studies on rodent beta-cells have suggested a role for GLUT2 and glucokinase in this control function and in mechanisms leading to diabetes. Little direct evidence exists so far to implicate these two proteins in glucose...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: De Vos, A, Heimberg, H, Quartier, E, Huypens, P, Bouwens, L, Pipeleers, D, Schuit, F
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1995
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185903/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7593639/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118308
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