Distinct roles for B7-1 (CD-80) and B7-2 (CD-86) in the initiation of experimental allergic encephalomyelitis.

The activation and differentiation of T cells require both antigen/MHC recognition and costimulatory signals. The present studies examined the role of B7-1 (CD80) and B7-2 (CD86) costimulation in the prototypic autoimmune disorder, experimental allergic encephalomyelitis (EAE). In adoptively transfe...

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izdano v:	J Clin Invest
Principais autores:	Racke, M K, Scott, D E, Quigley, L, Gray, G S, Abe, R, June, C H, Perrin, P J
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Clinical Investigation 1995
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185869/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7593605/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118274
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