Enhanced collagen synthesis and transcription by peak E, a contaminant of L-tryptophan preparations associated with the eosinophilia myalgia syndrome epidemic.

The pathogenesis of the eosinophilia myalgia syndrome (EMS) remains unclear. Several abnormal constituents have been found in the L-tryptophan lots responsible for the illness, particularly, 1,1-ethylidenebis[L-tryptophan], also called peak E or EBT, and 3-phenylamino-alanine or peak 5. However, the...

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Pubblicato in:	J Clin Invest
Autori principali:	Takagi, H, Ochoa, M S, Zhou, L, Helfman, T, Murata, H, Falanga, V
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185860/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7593596/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118265
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