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Tumors associated with p53 germline mutations: a synopsis of 91 families.

Although inherited p53 mutations are present in all somatic cells, malignant transformation is limited to certain organs and target cells. The analysis of 475 tumors in 91 families with p53 germline mutations reported since 1990 shows that breast carcinomas are most frequent (24.0%), followed by bon...

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Hlavní autoři: Kleihues, P., Schäuble, B., zur Hausen, A., Estève, J., Ohgaki, H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1858532/
https://ncbi.nlm.nih.gov/pubmed/9006316
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