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Recombinant ob protein reduces feeding and body weight in the ob/ob mouse.

To determine whether the product of the recently cloned ob gene functions as an adipose-related satiety factor, recombinant murine ob protein was administered intraperitoneally to ob/ob mice. Monomeric ob protein given as single morning injections to groups of three animals at seven doses ranging fr...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Weigle, D S, Bukowski, T R, Foster, D C, Holderman, S, Kramer, J M, Lasser, G, Lofton-Day, C E, Prunkard, D E, Raymond, C, Kuijper, J L
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185845/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7560100/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118254
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