Transduction of human trophoblastic cells by replication-deficient recombinant viral vectors. Promoting cellular differentiation affects virus entry.

We investigated the transfer of the lacZ reporter gene into human trophoblastic cells using herpes simplex virus and adeno-associated virus vectors. We used an established choriocarcinoma cell line (BeWo cells) that can be induced to terminally differentiate after treatment with cyclic-AMP. Our resu...

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Detalhes bibliográficos
Main Authors: Parry, S., Holder, J., Halterman, M. W., Weitzman, M. D., Davis, A. R., Federoff, H., Strauss, J. F.
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1858445/
https://ncbi.nlm.nih.gov/pubmed/9626056
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