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Matrix vesicles in osteomalacic hypophosphatasia bone contain apatite-like mineral crystals.
Hypophosphatasia, a heritable disease characterized by deficient activity of the tissue nonspecific isoenzyme of alkaline phosphatase (TNSALP), results in rickets and osteomalacia. Although identification of TNSALP gene defects in hypophosphatasia establishes a role of ALP in skeletal mineralization...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
1997
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1858375/ https://ncbi.nlm.nih.gov/pubmed/9403706 |
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