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Matrix vesicles in osteomalacic hypophosphatasia bone contain apatite-like mineral crystals.

Hypophosphatasia, a heritable disease characterized by deficient activity of the tissue nonspecific isoenzyme of alkaline phosphatase (TNSALP), results in rickets and osteomalacia. Although identification of TNSALP gene defects in hypophosphatasia establishes a role of ALP in skeletal mineralization...

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Detalles Bibliográficos
Main Authors: Anderson, H. C., Hsu, H. H., Morris, D. C., Fedde, K. N., Whyte, M. P.
Formato: Artigo
Idioma:Inglês
Publicado: 1997
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1858375/
https://ncbi.nlm.nih.gov/pubmed/9403706
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