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Vitronectin enhances internalization of crocidolite asbestos by rabbit pleural mesothelial cells via the integrin alpha v beta 5.

The mechanism by which pleural mesothelial cells, the likely progenitor cells of asbestos-induced mesothelioma, recognize and internalize crocidolite asbestos is unknown. Because incubation of asbestos fibers with serum increases their association with cells, we asked whether a protein coat on asbes...

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Pubblicato in:J Clin Invest
Autori principali: Boylan, A M, Sanan, D A, Sheppard, D, Broaddus, V C
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1995
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185837/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7560092/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118246
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