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Comparative distribution of the alpha 1(IV), alpha 5(IV), and alpha 6(IV) collagen chains in normal human adult and fetal tissues and in kidneys from X-linked Alport syndrome patients.

We have shown previously that the 5' ends of the genes for the alpha 5(IV) and alpha 6(IV) collagen chains lie head-to-head on Xq22 and are deleted in patients with Alport syndrome (AS)-associated diffuse leiomyomatosis. In this study, we raised a rabbit anti-human alpha 6(IV)chain antibody, demonst...

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Published in:J Clin Invest
Main Authors: Peissel, B, Geng, L, Kalluri, R, Kashtan, C, Rennke, H G, Gallo, G R, Yoshioka, K, Sun, M J, Hudson, B G, Neilson, E G
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1995
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185832/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7560087/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118241
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