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RNA synthesis and splicing interferes with DNA in situ end labeling techniques used to detect apoptosis.

The detection of DNA fragmentation by the use of the TUNEL technique has become a standard technique for the detection of apoptosis in tissue sections. DNA cleavage, detected by the TUNEL technique, is the last irreversible stage of the apoptosis cascade. When the nuclear DNA is cleaved in oligonucl...

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Detalhes bibliográficos
Main Authors: Kockx, M. M., Muhring, J., Knaapen, M. W., de Meyer, G. R.
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1858249/
https://ncbi.nlm.nih.gov/pubmed/9546348
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