Lacrimal gland inflammation is responsible for ocular pathology in TGF-beta 1 null mice.

Mice homozygous for a nonfunctional transforming growth factor-beta 1 gene develop rampant inflammation in vital organs that contributes to a shortened life span. The presence of circulating anti-nuclear anti-bodies, immune deposits in tissues, leukocyte infiltration, and increased major histocompat...

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Dades bibliogràfiques
Autors principals: McCartney-Francis, N. L., Mizel, D. E., Frazier-Jessen, M., Kulkarni, A. B., McCarthy, J. B., Wahl, S. M.
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1858095/
https://ncbi.nlm.nih.gov/pubmed/9358754
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