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Mice lacking the thrombin receptor, PAR1, have normal skin wound healing.

Thrombin's actions on platelets, macrophages, fibroblasts, and endothelial cells have prompted the hypothesis that thrombin may be important for inflammatory and fibroproliferative processes in wound healing. Protease-activated receptor 1 (PAR1) is a G-protein-coupled receptor that mediates man...

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Autors principals: Connolly, A. J., Suh, D. Y., Hunt, T. K., Coughlin, S. R.
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1858088/
https://ncbi.nlm.nih.gov/pubmed/9358744
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