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Systemic activation of the vascular endothelial growth factor receptor KDR/flk-1 selectively triggers endothelial cells with an angiogenic phenotype.

The hypothesis that tumor growth is angiogenesis dependent has been documented by a considerable body of direct and indirect experimental data. A prerequisite for the development of novel anti-angiogenic agents is the design of drugs that would be active only on those endothelial cells with an angio...

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Hlavní autoři: Ortéga, N., Jonca, F., Vincent, S., Favard, C., Ruchoux, M. M., Plouët, J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 1997
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1858082/
https://ncbi.nlm.nih.gov/pubmed/9358746
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