Insulin and insulin-like growth factor-I enhance human skeletal muscle protein anabolism during hyperaminoacidemia by different mechanisms.

Insulin inhibits proteolysis in human muscle thereby increasing protein anabolism. In contrast, IGF-I promotes muscle protein anabolism principally by stimulating protein synthesis. As increases or decreases of plasma amino acids may affect protein turnover in muscle and also alter the muscle's resp...

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Publié dans:	J Clin Invest
Auteurs principaux:	Fryburg, D A, Jahn, L A, Hill, S A, Oliveras, D M, Barrett, E J
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1995
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185808/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7560063/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118217
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