Thrombopoietin expands erythroid progenitors, increases red cell production, and enhances erythroid recovery after myelosuppressive therapy.

Thrombopoietin (TPO), the ligand for the receptor protooncogene c-mpl, has been cloned and shown to be the critical regulator of platelet production. Several features of c-Mpl expression, including its presence on erythroid cell lines, and the panmyeloid transformation characteristic of myeloprolife...

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Autores principales: Kaushansky, K, Broudy, V C, Grossmann, A, Humes, J, Lin, N, Ren, H P, Bailey, M C, Papayannopoulou, T, Forstrom, J W, Sprugel, K H
Formato: Artigo
Lenguaje:Inglês
Publicado: 1995
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC185797/
https://ncbi.nlm.nih.gov/pubmed/7657840
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