Hepatitis B virus (HBV) sequence variation of cytotoxic T lymphocyte epitopes is not common in patients with chronic HBV infection.

It has been suggested that immune selection pressure exerted by the cytotoxic T lymphocyte (CTL) response could be responsible for viral persistence during chronic hepatitis B virus infection. To address this question, in the current study we compared the DNA and amino acid sequences of, and the CTL...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Rehermann, B, Pasquinelli, C, Mosier, S M, Chisari, F V
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185778/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7544809/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118191
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