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Relationship of the 37,000- and 40,000-M(r) tryptic fragments of islet antigens in insulin-dependent diabetes to the protein tyrosine phosphatase-like molecule IA-2 (ICA512).

Sera from patients with insulin-dependent diabetes immunoprecipitate 64,000-M(r) proteins, distinct from glutamate decarboxylase, that are cleaved to 37,000- and 40,000-M(r) fragments by trypsin. We investigated possible relationships between 37,000- or 40,000-M(r) fragments of antigen and the tyros...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Payton, M A, Hawkes, C J, Christie, M R
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1995
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185775/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7657822/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118188
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