Detection of platelet-derived growth factor (PDGF)-AA in actively healing human wounds treated with recombinant PDGF-BB and absence of PDGF in chronic nonhealing wounds.

Some human chronic dermal wounds treated with recombinant platelet-derived growth factor-BB (rPDGF-BB) show increased healing coupled with fibroblast activation and granulation tissue formation. To determine whether endogenous PDGF is associated with healing and nonhealing dermal ulcer phenotypes, w...

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Pubblicato in:	J Clin Invest
Autori principali:	Pierce, G F, Tarpley, J E, Tseng, J, Bready, J, Chang, D, Kenney, W C, Rudolph, R, Robson, M C, Vande Berg, J, Reid, P
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185756/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7657809/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118169
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