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Maturational regulation of globotriaosylceramide, the Shiga-like toxin 1 receptor, in cultured human gut epithelial cells.

Differentiated villus intestinal epithelial cells express globotriaosylceramide, the Shiga-like toxin 1 (SLT-1) receptor, and are sensitive to toxin-mediated cytotoxicity, whereas undifferentiated crypt cells neither express Gb3 nor respond to toxin. To investigate if SLT-1 receptors are maturationa...

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Publicado en:J Clin Invest
Autores principales: Jacewicz, M S, Acheson, D W, Mobassaleh, M, Donohue-Rolfe, A, Balasubramanian, K A, Keusch, G T
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 1995
Materias:
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185755/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7657808/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118168
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