Entamoeba histolytica trophozoites induce an inflammatory cytokine response by cultured human cells through the paracrine action of cytolytically released interleukin-1 alpha.

Infection with the protozoan parasite Entamoeba histolytica results in a high mortality worldwide. To initiate infection, E. histolytica trophozoites in the bowel lumen penetrate the epithelium, and cause extensive lysis of host cells. The acute amebic lesions in animal models are characterized by i...

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Pubblicato in:	J Clin Invest
Autori principali:	Eckmann, L, Reed, S L, Smith, J R, Kagnoff, M F
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185748/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7657801/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118161
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