Transgenic overexpression of connexin50 induces cataracts

To examine the effects of increased expression of Cx50 in the mouse lens, transgenic mice were generated using a DNA construct containing the human Cx50 coding region and a C-terminal FLAG epitope driven by the chicken βB1-crystallin promoter. Expression of this protein in paired Xenopus oocytes ind...

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Main Authors: Chung, June, Berthoud, Viviana M., Novak, Layne, Zoltoski, Rebecca, Heilbrunn, Benjamin, Minogue, Peter J., Liu, Xiaoqin, Ebihara, Lisa, Kuszak, Jer, Beyer, Eric C.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1857337/
https://ncbi.nlm.nih.gov/pubmed/17217947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2006.11.004
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