Activity of Ketoconazole and Its Deacyl Derivative Against Plasmodium falciparum and Candida Isolates

Deacylketoconazole was 15- to 50-fold more active against Plasmodium falciparum than was ketoconazole, based on [(3)H]hypoxanthine uptake and quantitative parasite counts. In contrast, there were no significant differences between these drugs in their activity against clinical isolates of Candida sp...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Pfaller, Michael A., Segal, Joseph J., Krogstad, Donald J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1982
Assuntos:	Experimental Therapeutics
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185686/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6295271/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.22.5.917
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