Prevention of experimental colitis by parenteral administration of a pathogen‐derived immunomodulatory molecule

BACKGROUND: Filamentous haemagglutinin (FHA) of Bordetella pertussis subverts host immune responses by inhibiting interleukin (IL)12 and enhancing IL10 production by macrophages and dendritic cells, and promoting the induction of regulatory T cells. HYPOTHESIS: Injection of FHA would ameliorate dise...

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Detalhes bibliográficos
Main Authors: Braat, Henri, McGuirk, Peter, Kate, Fiebo J W Ten, Huibregtse, Inge, Dunne, Padraic J, Hommes, Daan W, Van Deventer, Sander J H, Mills, Kingston H G
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2007
Assuntos:
Colonic Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1856816/
https://ncbi.nlm.nih.gov/pubmed/16952913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2006.099861
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