7-Hydroxytropolone: an inhibitor of aminoglycoside-2"-O-adenylyltransferase.

Aminoglycoside-2"-O-adenylyltransferase was inhibited by 7-hydroxytropolone. Inhibition was competitive with respect to the cosubstrate ATP and appeared to require the unique vicinal arrangement of oxygens found in 7-hydroxytropolone. Combinations of 7-hydroxytropolone plus the appropriate amin...

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Detalles Bibliográficos
Main Authors: Allen, N E, Alborn, W E, Hobbs, J N, Kirst, H A
Formato: Artigo
Idioma:Inglês
Publicado: 1982
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC185667/
https://ncbi.nlm.nih.gov/pubmed/6185088
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