Increased CD4(+) CD25(+) T Regulatory Cell Activity in Trauma Patients Depresses Protective T(h)1 Immunity

OBJECTIVES: We recently reported increased CD4(+) CD25(+) T regulatory (Treg) activity after burn injury in mice. This study sought to determine if Tregs mediate the reduction in T(H)1-type immunity after serious injury in man and if Treg function is altered by injury. METHODS: Peripheral blood was...

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Detalhes bibliográficos
Main Authors: MacConmara, Malcolm P., Maung, Adrian A., Fujimi, Satoshi, McKenna, Ann M., Delisle, Adam, Lapchak, Peter H., Rogers, Selwyn, Lederer, James A., Mannick, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Original Articles and Discussions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1856576/
https://ncbi.nlm.nih.gov/pubmed/16998360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.sla.0000239031.06906.1f
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