Effect of decreased renal function on the pharmacokinetics of ceftazidime.

The pharmacokinetics of ceftazidime after a 1-g bolus dose were studied in 11 subjects, with creatinine clearances ranging from 113 to 6 ml/min. Concentrations of ceftazidime in serum were determined by microbiological assay. These data were fitted to a two-compartment open model, and pharmacokineti...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Ackerman, B H, Ross, J, Tofte, R W, Rotschafer, J C
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1984
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185645/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6378087/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.25.6.785
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