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Pulmonary deposition and clearance of aerosolized interferon.

Small particle aerosols of a hybrid DNA recombinant human alpha interferon, A/D bgl, and a related DNA recombinant leukocyte interferon, A, were generated and delivered to mice for 23.5 h a day for 4 consecutive days. The antiviral activity of these interferons in delivery reservoirs, in the aerosol...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Wyde, P R, Wilson, S Z, Kramer, M J, Sun, C S, Knight, V
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1984
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185631/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6742817/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.25.6.729
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