Overexpression of Bcl‐2 by activated human hepatic stellate cells: resistance to apoptosis as a mechanism of progressive hepatic fibrogenesis in humans

BACKGROUND AND AIMS: Myofibroblast‐like cells, originating from activation of hepatic stellate cells (HSC/MFs), play a key role in liver fibrosis, a potentially reversible process that may rely on induction of HSC/MFs apoptosis. While this possibility has been shown in cultured rat HSC, very limited...

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Autors principals: Novo, E, Marra, F, Zamara, E, Bonzo, L Valfrè di, Monitillo, L, Cannito, S, Petrai, I, Mazzocca, A, Bonacchi, A, De Franco, R S M, Colombatto, S, Autelli, R, Pinzani, M, Parola, M
Format: Artigo
Idioma:Inglês
Publicat: BMJ Group 2006
Matèries:
Liver Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1856252/
https://ncbi.nlm.nih.gov/pubmed/16423888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2005.082701
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