Anti‐ghrelin Spiegelmer NOX‐B11 inhibits neurostimulatory and orexigenic effects of peripheral ghrelin in rats

BACKGROUND AND AIMS: Ghrelin, the natural ligand of the growth hormone secretagogue receptor 1a, is the most powerful peripherally active orexigenic agent known. In rodents, ghrelin administration stimulates growth hormone release, food intake, and adiposity. Because of these effects, blocking of gh...

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Autori principali: Kobelt, P, Helmling, S, Stengel, A, Wlotzka, B, Andresen, V, Klapp, B F, Wiedenmann, B, Klussmann, S, Mönnikes, H
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Group 2006
Soggetti:
Stomach
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1856241/
https://ncbi.nlm.nih.gov/pubmed/15994217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2004.061010
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