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Iron loading and morbidity among relatives of HFE C282Y homozygotes identified either by population genetic testing or presenting as patients

BACKGROUND AND AIMS: Although most cases of hereditary haemochromatosis are associated with homozygosity for the C282Y mutation of the HFE gene, clinical penetrance varies and other genes may modify disease expression. If so, relatives from clinically affected families, by inheriting such genes, may...

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Detalhes bibliográficos
Main Authors: McCune, C A, Ravine, D, Carter, K, Jackson, H A, Hutton, D, Hedderich, J, Krawczak, M, Worwood, M
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1856156/
https://ncbi.nlm.nih.gov/pubmed/16174659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2005.070342
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