Reduced telomere length in rheumatoid arthritis is independent of disease activity and duration

BACKGROUND: Rheumatoid arthritis (RA) is associated with reduced lifespan and shortened telomere length in lymphocytes, but the mechanism underlying this is unclear. Telomere loss in white blood cells (WBC) is accelerated by oxidative stress and inflammation in vitro. It was postulated that the acce...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Steer, Sophia E, Williams, Frances M K, Kato, Bernet, Gardner, Jeffry P, Norman, Paul J, Hall, Margaret A, Kimura, Masayuki, Vaughan, Robert, Aviv, Abraham, Spector, Tim D
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Group 2007
Schlagworte:
Extended Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1856061/
https://ncbi.nlm.nih.gov/pubmed/17114192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2006.059188
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