High anti‐collagen type‐II antibody levels and induction of proinflammatory cytokines by anti‐collagen antibody‐containing immune complexes in vitro characterise a distinct rheumatoid arthritis phenotype associated with acute inflammation at the time of disease onset

OBJECTIVE: To investigate whether the cytokine‐inducing properties of surface‐bound collagen type II (CII)‐containing immune complexes (IC), which were reported earlier, have any clinical impact. METHODS: Anti‐CII serology was analysed in 274 patients with early rheumatoid arthritis (RA). Patients w...

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Hlavní autoři: Mullazehi, Mohammed, Mathsson, Linda, Lampa, Jon, Rönnelid, Johan
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Group 2007
Témata:
Concise Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1856042/
https://ncbi.nlm.nih.gov/pubmed/17040962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2006.064782
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