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Inactivation of the Mismatch Repair System in Pseudomonas aeruginosa Attenuates Virulence but Favors Persistence of Oropharyngeal Colonization in Cystic Fibrosis Mice

The inactivation of the mismatch repair (MMR) system of Pseudomonas aeruginosa modestly reduced in vitro fitness, attenuated virulence in murine models of acute systemic and respiratory infections, and decreased the initial oropharyngeal colonization potential. In contrast, the inactivation of the M...

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Bibliografiske detaljer
Main Authors: Mena, Ana, Maciá, María D., Borrell, Nuria, Moya, Bartolomé, de Francisco, Teresa, Pérez, José L., Oliver, Antonio
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855878/
https://ncbi.nlm.nih.gov/pubmed/17307847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00120-07
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