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Essentiality of Ribosomal and Transcription Antitermination Proteins Analyzed by Systematic Gene Replacement in Escherichia coli

We describe here details of the method we used to identify and distinguish essential from nonessential genes on the bacterial Escherichia coli chromosome. Three key features characterize our method: high-efficiency recombination, precise replacement of just the open reading frame of a chromosomal ge...

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Autori principali: Bubunenko, Mikhail, Baker, Teresa, Court, Donald L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855809/
https://ncbi.nlm.nih.gov/pubmed/17277072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01713-06
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