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“Cold-Sensitive” Mutants of the Lac Repressor

Thirteen of more than 4,000 single-amino-acid-replacement mutants of the Lac repressor, generated by suppression of amber nonsense mutants, were characterized as having a cold-sensitive phenotype. However, when expressed as missense mutations, none of the replacements cause cold sensitivity, implica...

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Autors principals: Barker, Andrew, Oehler, Stefan, Müller-Hill, Benno
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855763/
https://ncbi.nlm.nih.gov/pubmed/17172344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01462-06
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