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l-Valine Production with Pyruvate Dehydrogenase Complex-Deficient Corynebacterium glutamicum

Corynebacterium glutamicum was engineered for the production of l-valine from glucose by deletion of the aceE gene encoding the E1p enzyme of the pyruvate dehydrogenase complex and additional overexpression of the ilvBNCE genes encoding the l-valine biosynthetic enzymes acetohydroxyacid synthase, is...

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Autori principali: Blombach, Bastian, Schreiner, Mark E., Holátko, Jiří, Bartek, Tobias, Oldiges, Marco, Eikmanns, Bernhard J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855657/
https://ncbi.nlm.nih.gov/pubmed/17293513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02826-06
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