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Effect of the antimycotic drug naftifine on growth of and sterol biosynthesis in Candida albicans.

Naftifine, a new antimycotic drug of the allylamine class, is a potent inhibitor of ergosterol biosynthesis in Candida albicans. Treated cells showed a dose-dependent drop in ergosterol content; the level was reduced by 60% at concentrations of greater than 50 mg/liter, causing total inhibition of g...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Ryder, N S, Seidl, G, Troke, P F
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185557/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6375557/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.25.4.483
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