Fluoroquinolone Resistance in Streptococcus pneumoniae: Area Under the Concentration-Time Curve/MIC Ratio and Resistance Development with Gatifloxacin, Gemifloxacin, Levofloxacin, and Moxifloxacin

The potential for resistance development in Streptococcus pneumoniae secondary to exposure to gatifloxacin, gemifloxacin, levofloxacin, and moxifloxacin at various levels was examined at high inoculum (10(8.5) to 10(9) log(10) CFU/ml) over 96 h in an in vitro pharmacodynamic (PD) model using two flu...

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Hlavní autoři: LaPlante, Kerry L., Rybak, Michael J., Tsuji, Brian, Lodise, Thomas P., Kaatz, Glenn W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855487/
https://ncbi.nlm.nih.gov/pubmed/17296740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00646-06
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