Metronidazole plus Rifampin Sterilizes Long-Term Dormant Mycobacterium tuberculosis

Long-term nonreplicating (dormant) Mycobacterium tuberculosis populations (26-day-old cells) were sterilized by metronidazole plus rifampin, but not by metronidazole or rifampin alone, after 7 and 11 days of exposure to the drugs. Lower or no drug activity was observed against 19- or 12-day-old dorm...

Full description

Saved in:
Bibliographic Details
Main Authors: Iona, Elisabetta, Giannoni, Federico, Pardini, Manuela, Brunori, Lara, Orefici, Graziella, Fattorini, Lanfranco
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Susceptibility
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855463/
https://ncbi.nlm.nih.gov/pubmed/17242153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01468-06
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items