Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease

The major known genetic risk for Alzheimer's disease (AD), apolipoprotein E-4 (APOE-4), is associated with lowered parietal, temporal, and posterior cingulate cerebral glucose metabolism in patients with a clinical diagnosis of AD. To determine cognitive and metabolic decline patterns according...

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Main Authors: Small, Gary W., Ercoli, Linda M., Silverman, Daniel H. S., Huang, S.-C., Komo, Scott, Bookheimer, Susan Y., Lavretsky, Helen, Miller, Karen, Siddarth, Prabha, Rasgon, Natalie L., Mazziotta, John C., Saxena, Sanjaya, Wu, H. M., Mega, Michael S., Cummings, Jeffrey L., Saunders, Ann M., Pericak-Vance, Margaret A., Roses, Allen D., Barrio, Jorge R., Phelps, Michael E.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2000
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC18554/
https://ncbi.nlm.nih.gov/pubmed/10811879
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