Antagonism by chloramphenicol of broad-spectrum beta-lactam antibiotics against Klebsiella pneumoniae.

Chloramphenicol combined with cefotaxime, moxalactam, cefoperazone, aztreonam, or imipenem was tested in vitro against clinical isolates of Klebsiella pneumoniae. By time-kill cultures (killing curves), chloramphenicol interfered with activity of all five beta-lactams. When chloramphenicol was added...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Brown, T H, Alford, R H
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1984
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185539/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6375551/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.25.4.405
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