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Quantification of oxidative post-translational modifications of cysteine thiols of p21ras associated with redox modulation of activity using isotope-coded affinity tags (ICAT) and mass spectrometry
p21ras GTPase is the protein product of the most commonly mutated human oncogene and has been identified as a target for reactive oxygen and nitrogen species (ROS/RNS). Post-translational modification of reactive thiols, by reversible S-glutathiolation and S-nitrosation, and potentially also by irre...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1855198/ https://ncbi.nlm.nih.gov/pubmed/17320764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2006.12.012 |
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