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Short-Term Exposure of Multipotent Stromal Cells to Low Oxygen Increases Their Expression of CX3CR1 and CXCR4 and Their Engraftment In Vivo

The ability of stem/progenitor cells to migrate and engraft into host tissues is key to their potential use in gene and cell therapy. Among the cells of interest are the adherent cells from bone marrow, referred to as mesenchymal stem cells or multipotent stromal cells (MSC). Since the bone marrow e...

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Détails bibliographiques
Auteurs principaux: Hung, Shih-Chieh, Pochampally, Radhika R., Hsu, Shu-Ching, Sanchez, Cecelia, Chen, Sy-Chi, Spees, Jeffrey, Prockop, Darwin J.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855077/
https://ncbi.nlm.nih.gov/pubmed/17476338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000416
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